56701-24-7

Vestitol is the compound isolated from leaves of Trifolium arvense[1].

ChEBI: Vestitol is a member of the class of hydroxyisoflavans that is isoflavan substituted by hydroxy groups at positions 7 and 2' and a methoxy group at position 4'. Isolated from Glycyrrhiza uralensis, it exhibits anti-inflammatory activity. It has a role as an anti-inflammatory agent, a plant metabolite and a phytoalexin. It is an aromatic ether, a member of hydroxyisoflavans and a methoxyisoflavan.

Hydroxyisoflavan isolated from Cuban and Brazilian red propolis th at exhibits potent anti-inflammatoryanti-viraland antiparasitic activities.

(±)-Vestitol is a hydroxyisoflavan isolated from Cuban and Brazilian red propolislicorice root and other sources th at exhibits potent anti-inflammatoryanti-viraland antiparasitic activities. Apparently Vestitol inhibits release of the chemokines CXCL1/KC and CXCL2/MIP-2 from macrophages. Vestitol strongly inhibits Chikungunya virus infection. Vestitol exhibits anti-trypanosomal activity against T. brucei and T. congolense (EC50 3.86 and 4.36 μg/ml).

[1] John L. Ingham, et al. Notizen: Isoflavonoid Phytoalexins from Leaves of Trifolium arvense.