548-30-1

An a-naphthaphenanthridine alkaloid, this base occurs in the roots of Sanguinaria canadensis. It is separated from the remaining bases by chromatography and purified by crystallization from CHC13 followed by sublimation in a high vacuum. It is optically inactive and may also be prepared by oxidation of sanguinarine nitrate by potassium ferricyanide in alkaline solution. No salts of this alkaloid have been prepared.

Hydroxysanguinarine can be used to treat coronavirus infection.

ChEBI: Hydroxysanguinarine is a benzophenanthridine alkaloid.

Spiithetal., Ber., 70, 1677 (1936)
Schlemmer, Gempp., Arch. Pharm., 276,506 (1938)