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53123-88-9

Name Rapamycin
CAS 53123-88-9
EINECS(EC#) 610-965-5
Molecular Formula C33H31NO2
MDL Number MFCD00867594
Molecular Weight 473.6
MOL File 53123-88-9.mol

Chemical Properties

Appearance White to Off-White Solid
Melting point  183-185°C
Boiling point  799.83°C (rough estimate)
alpha  D25 -58.2° (methanol)
density  1.0352 (rough estimate)
vapor pressure  0.56 hPa ( 20 °C)
refractive index  1.5280 (estimate)
Fp  87 °C
storage temp.  -20°C
solubility  ethanol: soluble2MM
form  solution
pka 10.40±0.70(Predicted)
color  colorless to yellow
Water Solubility  Soluble in DMSO at 50mg/ml or methanol at 25mg/mlSoluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water.
Usage Used as an immunosuppressant
Sensitive  Moisture Sensitive/Light Sensitive/Hygroscopic
Merck  14,8114
Stability: Stable for 2 years? from date of purchase as supplied.? Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
CAS DataBase Reference 53123-88-9(CAS DataBase Reference)

Safety Data

Hazard Codes  Xi
Risk Statements 
R36/38:Irritating to eyes and skin .
Safety Statements 
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
RIDADR  UN 1648 3 / PGII
WGK Germany  2
RTECS  VE6250000
Autoignition Temperature 301 °C
HS Code  29419000
Hazardous Substances Data 53123-88-9(Hazardous Substances Data)
Toxicity
LD50 in mice (mg/kg): 600 i.p.; >2,500 orally (Vézina)

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