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Rapamycin

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53123-88-9 Basic informationMore
USE
Rapamycin is a triene macrolide discovered in 1974 as a metabolite of Streptomyces hygroscopicus found in a soil obtained on Rapa Nui (Easter Island). Rapamycin displayed potent and selective antifungal activity, notably against Candida albicans. Interest in the metabolite waned until the structural relationship to the potent immunosuppressant fujimycin (Antibiotic FK506) was recognised in the mid-1980s. This recognition led to the re-discovery of rapamycin as a highly selective antitumor and immunosuppressant. Rapamycin inhibits the activity of the protein, mTOR (mammalian target of rapamycin) which functions in a signalling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12). The rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signalling pathway.
Lastest Price from Rapamycin manufacturers
  • Rapamycin
  • US $999.00-666.00/kg
  • CAS:53123-88-9
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 5000
  • 2024-12-22
  • Rapamycin
  • US $150.00 /kg
  • CAS:53123-88-9
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 500kg
  • 2024-12-20

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  • Company Name:Shanghai Minkai Biological Technology Co., Ltd
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  • Company Name:Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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    Purity:>=99%;10mM*1mL in DMSO Package:10mg;25mg;1mL
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