Rapamycin
53123-88-9 Basic informationMore
- Product Name:Rapamycin
- Synonyms: AY 22989 23,27-EPOXY-3H-PYRIDO(2,1-C)(1,4)OXAAZACYCLOHENTRIACONTINE NSC-226080 RAPAMYCIN RAPAMYCIN, STREPTOMYCES HYGROSCOPICUS RPM antibioticay22989 (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
- CAS:53123-88-9
- MF:C51H79NO13
- MW:914.17
- EINECS:610-965-5
- Mol File:53123-88-9.mol
USE
Rapamycin is a triene macrolide discovered in 1974 as a metabolite of Streptomyces hygroscopicus found in a soil obtained on Rapa Nui (Easter Island). Rapamycin displayed potent and selective antifungal activity, notably against Candida albicans. Interest in the metabolite waned until the structural relationship to the potent immunosuppressant fujimycin (Antibiotic FK506) was recognised in the mid-1980s. This recognition led to the re-discovery of rapamycin as a highly selective antitumor and immunosuppressant. Rapamycin inhibits the activity of the protein, mTOR (mammalian target of rapamycin) which functions in a signalling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12). The rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signalling pathway.
Lastest Price from Rapamycin manufacturers
- Rapamycin
- US $150.00 /kg
- CAS:53123-88-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 500kg
- 2024-11-21
- Sirolimus(Rapamycin)
- US $0.00 /g/Bag
- CAS:53123-88-9
- Min. Order: 10g
- Purity: 98%min
- Supply Ability: 20kg/month
- 2024-11-21
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- Company Name:Shanghai Minkai Biological Technology Co., Ltd
- Tel:021-021-52919136 17315815539
- Products Intro:Product Name:Sirolimus/Rapamycin
CAS:53123-88-9
Purity:99% HPLC Package:1g;1kg;10kg - CB Index:58
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- Company Name:Fujian Kerui Pharmaceutical Co., Ltd.
- Tel:+86-591-83309157; 18505919179
- Products Intro:Purity:DMF、GMP Package:CP Remarks:In House Standard More...
- CB Index:62
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- Company Name:Shanghai Arbor Chemical Co., Ltd.
- Tel:021-60451683 15021268886
- Products Intro:Product Name:RapaMycin
CAS:53123-88-9
Purity:98% Package:500g Remarks:500g More... - CB Index:55
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- Company Name:Shanghai Linka Biotechnology Co., Ltd.
- Tel: 15901858719
- Products Intro:Product Name:Sirolimus(Rapamycin)
CAS:53123-88-9
Purity:0.95 Package:10g;100g;1kg;5kg;25kg Remarks:10g;100g;1kg;5kg;25kg More... - CB Index:55
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- Company Name:Shanghai Hanjing Chemicals Co., Ltd.
- Tel:021-54285032 13641685631
- Products Intro:Product Name:Sirolimus
CAS:53123-88-9
Purity:98% Package:1G; 5G; 10G;100G;500G;1KG;10KG;100KG More... - CB Index:55
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- Company Name:Hubei wei shi reagent group ltd., company
- Tel:027-59102966 18717199209
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CAS:53123-88-9
Purity:95% Package:1瓶/RMB 758 - CB Index:58
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- Company Name:Shengbaolai Biotechnology Co., Ltd
- Tel:86-027-59105235 15527244834
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Purity:99% Package:001kg;01kg - CB Index:58
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- Company Name:Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
- Tel:021-59167510 18117107507
- Products Intro:Product Name:Rapamycin
CAS:53123-88-9
Purity:>=99%;10mM*1mL in DMSO Package:10mg;25mg;1mL - CB Index:58
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