518-96-7

This alkaloid is very hygroscopic and difficult to obtain crystalline. It occurs in the roots of Dictamnus albus and is somewhat unstable, turning red on exposure to light. Isolation under mild conditions show it to be a true alkaloid and not an artifact.

Isomaculosidine is an alkaloid that can be isolated from D. dasycarpus. Isomaculosidine can inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 microglial cells[1].

Gellert et al., Herba Hung., 10, 123 (1971) Storer, Young., Tetrahedron, 29, 1217 (1973)