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485-49-4

Supplier Related Products Identification Chemical Properties Safety Data Material Safety Data Sheet(MSDS) Spectrum Detail Well-known Reagent Company Product Information

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Identification

Name
(+)-Bicuculline
CAS
485-49-4
Synonyms
(+)-BICUCULINE
(+)-BICUCULLINE
BICUCULLINE
D-BICUCULLINE
(r-(r*,s*))-6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-furo(3,4-e)-1,3-benzodioxol-8(6h)-one
[R-(R*,S*)]-6-(5,6,7,8-TETRAHYDRO-6-METHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLIN-5-YL)FURO[3,4-E]-1,3-BENZODIOXOL-8(6H)-ONE
5-g)isoquinolin-5-yl)-,(r-(r*,s*))-lo(
bicucullin
furo(3,4-e)-1,3-benzodioxol-8(6h)-one,6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxo
PLUS-BICUCULLINE
(+)-BICUCULLINE 1(S),9(R)
(6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]lisoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one
NSC 3219
(+)-Bicuculline
(R-(R*,S*))-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-furo(3,4-e)-1,3-benzodioxol-8(6H)-one
NSC 32192)
(6R)-6-[(5S)-6-Methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[4,3-g][1,3]benzodioxol-8-one
1,3-Dioxolo[4,5-g]isoquinoline, furo[3,4-e]-1,3-benzodioxol-8(6H)-one deriv.
Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g) isoquinolin-5-yl)-, (R-(R*,S*))-
(6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one
EINECS(EC#)
207-619-7
Molecular Formula
C20H17NO6
MDL Number
MFCD00005006
Molecular Weight
367.35
MOL File
485-49-4.mol

Chemical Properties

Appearance
Pale Yellow Solid
mp 
193-197 °C

storage temp. 
0-6°C
Usage
Alkaloid naturally occurring in the d-form. Shows GABA antagonist activity.
Merck 
13,1207
CAS DataBase Reference
485-49-4(CAS DataBase Reference)
Storage Precautions
Air sensitive;Light sensitive
EPA Substance Registry System
485-49-4(EPA Substance)

Safety Data

Hazard Codes 
T,N,Xn
Risk Statements 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R50:Very Toxic to aquatic organisms.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
Safety Statements 
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
RIDADR 
UN 1544 6.1/PG 2

WGK Germany 
3

RTECS 
LV0909840


10-23
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29399990

Material Safety Data Sheet(MSDS)

Spectrum Detail

Well-known Reagent Company Product Information

Sigma Aldrich
485-49-4(sigmaaldrich)
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