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480-40-0

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Identification

Name
Chrysin
CAS
480-40-0
Synonyms
5,7-dihydroxy-2-phenyl-4h-benzo[b]pyran-4-one
5,7-DIHYDROXY-2-PHENYL-CHROMEN-4-ONE
5,7-DIHYDROXYFLAVONE
AKOS NCG1-0026
CHRYSIN
CHRYSINE
LABOTEST-BB LT00440772
5,7-dihydroxy-2-phenyl-4h-1-benzopyran-4-on
5,7-dihydroxy-2-phenyl-4h-1-benzopyran-4-one
5,7-dihydroxy-flavon
Chrysin, 99+%
CHRYSIN(RG)
5,7-DIHYDROXYFLAVONE(CHRYSIN)
Chrysin 5,7-
Chrysin 99.0%min
CHRYSIN (5,7-HYDROXYFLAVONE)
Chrysin Extract
4H-1-Benzopyran-4-one,5,7-dihydroxy-2-phenyl-
Chrysidenon 1438
EINECS(EC#)
207-549-7
Molecular Formula
C17H14O7
MDL Number
MFCD00006834
Molecular Weight
330.29
MOL File
480-40-0.mol

Chemical Properties

Appearance
beige powder
Melting point 
284-286 °C(lit.)

mp 
284-286 °C(lit.)

Boiling point 
357.45°C (rough estimate)
density 
1.2693 (rough estimate)
refractive index 
1.4872 (estimate)
storage temp. 
0-6°C
form 
Crystalline Powder
pka
6.50±0.40(Predicted)
color 
Yellow
Stability:
Stable. Incompatible with strong oxidizing agents.
Merck 
14,2256
BRN 
233276
InChIKey
RTIXKCRFFJGDFG-UHFFFAOYSA-N
CAS DataBase Reference
480-40-0(CAS DataBase Reference)

Safety Data

Hazard Codes 
Xi
Risk Statements 
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
WGK Germany 
3

RTECS 
LK8329050


10
HazardClass 
IRRITANT
HS Code 
29329900

Raw materials And Preparation Products

Material Safety Data Sheet(MSDS)

Hazard Information

Description
Chrysin is a natural flavonoid with antioxidant, anti-inflammatory, and anticancer properties. It blocks COX-2 gene expression, PGE2 production, and hydroxyl radical formation in LPS-induced RAW 264.7 cells. Chrysin inhibits insulin-induced HIF-1α expression (~50% at 10 μM) in human prostate cancer DU145 cells and blocks DU145 xenograft-induced angiogenesis in vivo. In a mouse model of ischemia/reperfusion injury, chrysin decreased pro-inflammatory gene expression and oxidative stress, resulting in a reduction of infarct volume and neurological defects.
Chemical Properties
beige powder
Uses
diuretic
Uses
Chrysin is a flavanoid with anti-inflammatory effect and potential protective effects against cancer and cardiovascular disease. Studies show that Chrysin is central benzodiazepine receptor ligand wit h possible anxiolytic effects. Chrysin was initially believed to have aromatase inhibitor but recent in vivo studies have disproved that.
Definition
ChEBI: A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7.

Spectrum Detail

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