480-00-2

Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from shallots.

Eleutherol is a naphthalene isolated from E. americana with antifungal activities[1]. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 μg/mL and 250 μg/mL[1]. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM[2].

ChEBI: Eleutherol is a naphthofuran.

[1] Adriana Campos, et al. Antifungal Activity of Pyranonaphthoquinones Obtained from Cipura paludosa Bulbs. Nat Prod Commun. 2015 Sep;10(9):1589-92. PMID:26594766
[2] Tomohiro Ieyama,et al.α-Glucosidase inhibitors from the bulb of Eleutherine americana. Food Chem.2011 Sep 15;128(2):308-11. DOI:10.1016/j.foodchem.2011.03.021