41432-97-7

Bleomycin A2, an antitumor antibiotic promoting DNA-degradation, is an aspartate/asparagine-β-hydroxylase (AspH) inhibitor with an IC50 of 1.47 μM[1].

Glycopeptide

[1] Lennart Brewitz, et al. Small-molecule active pharmaceutical ingredients of approved cancer therapeutics inhibit human aspartate/asparagine-β-hydroxylase. Bioorg Med Chem. 2020 Oct 15;28(20):115675. DOI:10.1016/j.bmc.2020.115675