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Name Doxorubicin hydrochloride
CAS 25316-40-9
EINECS(EC#) 246-818-3
Molecular Formula C27H30ClNO11
MDL Number MFCD00077757
Molecular Weight 579.98
MOL File 25316-40-9.mol

Chemical Properties

Appearance Adriamycin is an orange to red cake-like or needle-like crystalline solid.
Melting point  216 °C (dec.)(lit.)
alpha  D20 +248±2° (c = 0.1 in methanol)
storage temp.  2-8°C
solubility  H2O: 10 mg/mL, clear, red-orange
form  solid
pka pKa 8.25±0.60 (Uncertain);8.43±0.70 (Uncertain);11.9±0.4 (Uncertain);12.95±0.1 (Uncertain);13.8±0.70 (Uncertain)
color  orange to dark red
Water Solubility  Soluble in water.
Usage Used as an antineoplastic
λmax 497nm(H2O)(lit.)
Merck  13,3473
BRN  4229251
Stability: Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
CAS DataBase Reference 25316-40-9(CAS DataBase Reference)
EPA Substance Registry System 25316-40-9(EPA Substance)

Safety Data

Hazard Codes  T,T+,Xi
Risk Statements 
R45:May cause cancer.
R22:Harmful if swallowed.
R40:Limited evidence of a carcinogenic effect.
R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed .
Safety Statements 
S53:Avoid exposure-obtain special instruction before use .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S22:Do not breathe dust .
S7/9:Keep container tightly closed and in a well-ventilated place .
WGK Germany  3
RTECS  QI9295900
HS Code  29419090
LD50 i.v. in mice: 21.1 mg/kg (Bertazzoli, 1970)

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