ChemicalBook CAS DataBase List 351353-48-5

351353-48-5

Name	DPTIP
CAS	351353-48-5
Molecular Formula	C21H18N2O3S
MDL Number	MFCD34470276
Molecular Weight	378.44
MOL File	351353-48-5.mol

Chemical Properties

Boiling point	608.3±55.0 °C(Predicted)
density	1.292±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Solid
pka	9.27±0.25(Predicted)
color	Off-white to gray

Safety Data

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H335-H319
Precautionary statements	P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

Hazard Information

Spectrum Detail

Supplier

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Bide Pharmatech Ltd.

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Beijing Biocreative Technology Co., Ltd.

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Animal Model:	Mice^[1].
Dosage:	10?mg/kg.
Administration:	IP 0.5?h prior to IL-1β striatal injection.
Result:	Brain concentrations of DPTIP are above its IC50 for nSMase2 inhibition for at least 4?h after compound administration. The number of astrocyte-derived EVs was reduced by 51?±?13% 2?h post IL-1β administration.

351353-48-5

Chemical Properties

Safety Data

Hazard Information

Uses

in vivo

storage

References

Spectrum Detail

Supplier

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