Supplier Related Products Identification Chemical Properties Safety Data Hazard Information Spectrum Detail Well-known Reagent Company Product Information
WebSite >  CAS DataBase List  > 3006-96-0

3006-96-0

Supplier Related Products Identification Chemical Properties Safety Data Hazard Information Spectrum Detail Well-known Reagent Company Product Information

Product Image

Identification

Name
4-(Hydroxymethyl)benzoic acid
CAS
3006-96-0
Synonyms
4-CARBOXYBENZYL ALCOHOL
4-HYDROXYMETHYLBENZOIC ACID
HMBA
HMBA LINKER
RARECHEM AL BO 1443
HMBA LINKER,4-HYDROXYTHYLBENZOIC ACID
Hydroxymethylbenzoicacid
4-Hydroxythylbenzoic acid
hb linker
Benzoic acid, 4-(hydroxymethyl)-
4-(HYDROXYMETHYL)BENZOIC ACID HMBA LINKER 98%
4-(HYDROXYMETHYL)BENZOIC ACID (HMBA LINKER)
4-(Hydroxymethyl)benzoic acid, 98+%
EINECS(EC#)
628-233-9
Molecular Formula
C8H8O3
MDL Number
MFCD00017598
Molecular Weight
152.15
MOL File
3006-96-0.mol

Chemical Properties

Melting point 
182-185 °C (lit.)
mp 
182-185 °C(lit.)

Boiling point 
140-150 °C(Press: 9 Torr)
density 
1.314±0.06 g/cm3(Predicted)
storage temp. 
2-8°C

pka
4.16±0.10(Predicted)
form 
Coarse Fibers
color 
White
BRN 
2690023
InChIKey
WWYFPDXEIFBNKE-UHFFFAOYSA-N
CAS DataBase Reference
3006-96-0(CAS DataBase Reference)

Safety Data

Hazard Codes 
Xi
Risk Statements 
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
WGK Germany 
3

HS Code 
29181990

Hazard Information

Chemical Properties
Off-white solid
Uses
This linkage reagent for SPPS is essentially acid stable. It is useful in combination with Fmoc-amino acids. Its peptide esters are usually cleaved by basic or nucleophilic reagents, especially by ammonia in the preparation of peptide amides.
Uses
4-(Hydroxymethyl)benzoic Acid is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive age nt.
Synthesis Reference(s)
Journal of the American Chemical Society, 107, p. 1365, 1985 DOI: 10.1021/ja00291a042

Spectrum Detail

Well-known Reagent Company Product Information

SupplierMore