156-28-5

2-Phenethylamine is a natural monoamine alkaloid that acts as neuromodulator in the central nervous system. It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases as well as other enzymes. This product is intended for forensic and research applications.

White to Light yellow powder to crystal. soluble in water, alcohol, ether.

CNS stimulant

In a nitrogen environment, add the aliphatic nitro derivatives (0.6mmol), pinacol borane (3.6mmol, 6.0equiv), tetrahydrofuran (2mL), triethylboron (5mol%), and potassium tert-butoxide (5mol %) into a 10mL sealed tube and then place it in a 100 oil bath with heating and stirring for 24 hours. At the end of the reaction, add 2mL of 1M hydrochloric acid aqueous solution to the reaction solution and stir at room temperature for 6h. Finally, 2-Phenylethylamine hydrochloride is obtained by filtration.

Poison by skin contact, subcutaneous, and intravenous routes. A human eye irritant. A skin irritant and possible sensitizer. Human systemic effects by ingestion: blood pressure lowering, anorexia. When heated to decomposition it emits very toxic fumes of

[1] MASATO NAKAMURA  Daiichiro N  Akira Ishii. Characterization of β-phenylethylamine-induced monoamine release in rat nucleus accumbens: a microdialysis study[J]. European journal of pharmacology, 1998, 349 2: Pages 163-169. DOI: 10.1016/s0014-2999(98)00191-5
[2] H Y YANG  N H N. Beta-phenylethylamine: a specific substrate for type B monoamine oxidase of brain.[J]. Journal of Pharmacology and Experimental Therapeutics, 1973, 187 2: 365-371.
[3] O. SUZUKI  M. O  Y Katsumata. Oxidation of β-Phenylethylamine by Both Types of Monoamine Oxidase: Examination of Enzymes in Brain and Liver Mitochondria of Eight Species[J]. Journal of Neurochemistry, 1981, 36 3: 1298-1301. DOI: 10.1111/j.1471-4159.1981.tb01734.x