150148-81-5

Strictosidinic acid, an orally active glycoside indole monoterpene alkaloid isolated from Psychotria myriantha leaves, inhibits precursor enzymes of 5-HT biosynthesis and reduces the 5-HT levels. Strictosidinic acid has peripheral analgesic and antipyretic activities in mice[1][2].

Strictosidinic acid, an glycosidic indole monoterpene alkaloid isolated from the leaves of Psychotria myriantha, inhibits the precursor enzymes of 5-HT biosynthesis and reduces 5-HT content. It has peripheral analgesic and antipyretic activity in mice.

5-HT Receptor

5-HT Receptor

[1] F M Farias, et al. Strictosidinic Acid, Isolated From Psychotria Myriantha Mull. Arg. (Rubiaceae), Decreases Serotonin Levels in Rat Hippocampus. Fitoterapia. 2012 Sep;83(6):1138-43. DOI:10.1016/j.fitote.2012.04.013
[2] F M Farias, et al. Monoamine Levels in Rat Striatum After Acute Intraperitoneal Injection of Strictosidinic Acid Isolated From Psychotria Myriantha Mull. Arg. (Rubiaceae). Phytomedicine. 2010 Mar;17(3-4):289-91. DOI:10.1016/j.phymed.2009.05.008