BE-18591 shows antimicrobial activity against gram-positive and some gram-negative bacteria. BE-18591 inhibited the growth of the MKN-45 cell line (IC50= 0.285 μg/mL) and the P388 cell line (IC50= 0.52 μg/mL)[1].
References
[1] K Kojiri, et al. A new antitumor substance, BE-18591, produced by a streptomycete. I. Fermentation, isolation, physico-chemical and biological properties. J Antibiot (Tokyo). 1993 Dec;46(12):1799-803. DOI:10.7164/antibiotics.46.1799
