Baringolin is a thiopeptide antibiotic from Kocuria palustris. Baringolin is effective against methicillin-?resistant Staphylococcus aureus.
in vivo
Kocurin (1.25-10 mg/kg; intravenous injection; single dose) has the 100% effective dose (ED100) values of 2.5 and 5.0 mg/kg for MRSA, and an ED100 value of 10.0 mg/kg for VRE in the BALB/c mouse septicemia model[1].
