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13292-46-1

Name Rifampicin
CAS 13292-46-1
EINECS(EC#) 236-312-0
Molecular Formula C43H58N4O12
MDL Number MFCD00151389
Molecular Weight 822.94
MOL File 13292-46-1.mol

Chemical Properties

Appearance Red to Orange Crystalline Solid
Melting point  183°C (dec.)
Boiling point  761.02°C (rough estimate)
density  1.1782 (rough estimate)
refractive index  1.6000 (estimate)
storage temp.  2-8°C
solubility  chloroform: soluble50mg/mL, clear
form  crystalline
pka 1.7, 7.9(at 25℃)
color  faint red to very dark red
Water Solubility  Soluble in DMSO or methanolSoluble in water, ethyl acetate, chloroform, methanol, tetrahydrofuran and dimethyl sulfoxide.
Merck  14,8216
BRN  5723476
BCS Class 2
Stability: Hygroscopic, Light Sensitive
IARC 3 (Vol. 24, Sup 7) 1987
EPA Substance Registry System Rifamycin, 3-[[(4-methyl-1-piperazinyl) imino]methyl]-(13292-46-1)

Safety Data

Hazard Codes  Xn,Xi
Risk Statements 
Safety Statements 
WGK Germany  3
RTECS  VJ7000000
8-10-21
HS Code  29419000
Safety Profile
Suspected carcinogen with experimental neoplastigenic and teratogenic data. Poison by intraperitoneal and intravenous routes. Moderately toxic to humans by ingestion. Moderately experimentally toxic by ingestion and subcutaneous routes. Human systemic effects by ingestion: conjunctiva irritation, iritis (inflammation of the iris), other eye effects, dermatitis. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazardous Substances Data 13292-46-1(Hazardous Substances Data)
Toxicity
LD50 in mice, rats (mg/kg): 885, 1720 orally; 260, 330 i.v.; 640, 550 i.p. (Fürész)

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