Rifampicin

• Product Name:Rifampicin
• Synonyms: ,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,1/// 2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2-h)-dione,5,6 3-(((4-methyl-1-piperazinyl)imino)methyl)-rifamyci 3-((4-methyl-1-piperazinyl)iminomethyl)rifamycinsv 8-(((4-methyl-1-piperazinyl)imino)methyl)rifamycinsv 8-(4-Methylpiperazinyliminomethyl)rifamycinSV 8-(n-(4-methyl-1-piperazinyl)formidoyl)-rifomycins RIFAMPIN ''LEPETIT''
• CAS:13292-46-1
• MF:C43H58N4O12
• MW:822.94
• EINECS:236-312-0
• Mol File:13292-46-1.mol
• 

Rifampicin and other compounds of the ansamycin group specifically inhibit DNA-dependent RNA polymerase; that is, they prevent the transcription of RNA species from the DNA template. Rifampicin is an extremely efficient inhibitor of the bacterial enzyme, but fortunately eukaryotic RNA polymerase is not affected. RNA polymerase consists of a core enzyme made up of four polypeptide subunits, and rifampicin specifically binds to the β subunit where it blocks initiation of RNA synthesis, but is without effect on RNA polymerase elongation complexes. The structural mechanism for inhibition of bacterial RNA polymerase by rifampicin has recently been elucidated. The antibiotic binds to the β subunit in a pocket which directly blocks the path of the elongating RNA chain when it is two to three nucleotides in length. During initiation the transcription complex is particularly unstable and the binding of rifampicin promotes dissociation of short unstable RNA DNA hybrids from the enzyme complex. The binding pocket for rifampicin, which is absent in mammalian RNA polymerases, is some 12 Å away from the active site.

• Rifampicin
• 
• US $999.00-666.00/kg
• CAS:13292-46-1
• Min. Order: 1kg
• Purity: 99%
• Supply Ability: 5000
• 2024-11-23

• Rifampicin
• 
• US $0.00-0.00/Kg/Drum
• CAS:13292-46-1
• Min. Order: 1KG
• Purity: 97%-102%;BP
• Supply Ability: 500 KG
• 2024-11-22

• Company Name:Jiangxi ravel Biotechnology Co.,Ltd
• Tel:185-0276-2003 18502762003;
• Products Intro:Product Name:Rifampicin
  CAS:13292-46-1
  Purity:99%+ Package:1kg;10kg;25kg
• CB Index:58
• Related Information:Catalog(2306)

• Company Name:Wuhan kemike Biomedical Technology Co., Ltd
• Tel:027-87747081 18186681184
• Products Intro:Product Name:Rifampicin
  CAS:13292-46-1
  Purity:白色结晶粉末/98% Package:1kg 25kg
• CB Index:58
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• Company Name:Wuhan Fortuna Chemical Co., Ltd
• Tel:027-59207852 13308628970
• Products Intro:Product Name:Rifampicin
  CAS:13292-46-1
  Purity:99% Package:25kg/
• CB Index:58
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• Company Name:Hubei widely chemical technology Co., Ltd.
• Tel:027-59402396 13419635609
• Products Intro:Product Name:rifampicin
  CAS:13292-46-1
  Purity:98% Package:10克/RMB 500;5千克25千克 More...
• CB Index:55
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• Company Name:Jiangxi ravel Biotechnology Co.,Ltd
• Tel:400-880-2824 15608648206
• Products Intro:Product Name:Rifampicin
  CAS:13292-46-1
  Purity:98% Package:1kg;5kg;10kg
• CB Index:58
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• Company Name:Hubei wei shi reagent group ltd., company
• Tel:027-02759101766 13125137661
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  CAS:13292-46-1
  Purity:99%魏氏试剂 Package:1瓶
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• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
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• Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
• Tel:021-61259108 18621169109
• Products Intro:Product Name:RifaMpicin
  CAS:13292-46-1
  Purity:>98.0%(T) Package:5g;25g Remarks:R0079 More...
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