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1-Bromo-3-chloro-5-iodobenzene serves as a precursor in a chemoselective Suzuki–Miyaura cross-coupling route to tailored glasses, with palladium ligands chosen to direct selectivity among its three differently reactive C–halogen bonds [2].

1-Bromo-3-chloro-5-iodobenzene was prepared by an eight-step synthesis with benzene as the raw material. Each step requires only a short reaction time and the individual yields are in the range of 62-96%^[1].

[1] ADDISON AULT; Raymond K. 1-bromo-3-chloro-5-iodobenzene: An eight-step synthesis from benzene[J]. Journal of Chemical Education, 1966. DOI:10.1021/ed043p213.