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Carnitine plays an important role in metabolism in mammals, plants and some bacteria. L-carnitine is involved in fatty acid metabolism, transporting fatty acid chains into the mitochondrial matrix, allowing cells to obtain energy. When using deuterated L-carnitine-d9 as a standard for LC MS/MS, it is possible to determine the content of free carnitine in most biological fluids.

Carnitine and its derivatives are a diagnostic sign of disorders of β-oxidation of fatty acids. Isotopically labeled L-Carnitine-d9 is used to determine free carnitine in disease screening, for example: systemic carnitine deficiency, carnitine palmitoyl transferase deficiency.

L-Carnitine-d9 is the isotope labelled analog of L-Carnitine (C184110); an essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthesized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado.

ChEBI: ATP is an adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways. It has a role as a nutraceutical, a micronutrient, a fundamental metabolite and a cofactor. It is an adenosine 5'-phosphate and a purine ribonucleoside 5'-triphosphate. It is a conjugate acid of an ATP(3-).