≥24.8 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form
solid
pka
6.81±0.20(Predicted)
color
Light yellow to yellow
Description
MK-2461 is a potent inhibitor of c-Met, Ron, Flt1/3, PDGFRβ, Mer and FGFR1/2/3 with IC50 of 2.5 nM, 7 nM, 10 nM/22 nM, 22 nM, 24 nM and 65 nM/39 nM/50 nM, respectively.
