Fmoc-Gly-OH is an Fmoc protected glycine derivative useful for proteomics studies and solid phase peptide synthesis techniques. Glycine is the simplest, and least sterically hindered of the amino acids, which confers a high level of flexibility when incorporated into polypeptides. This compound could be useful for solid phase peptide synthesis and for coupling of saccharide β-glycosylamines used for the for the fractionation of oligosaccharides and formation of neoglycoconjugates.