Coenzyme?Q1

Описание

Cooenzyme Q₁₀ (CoQ₁₀) is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. CoQ₁ is an amphipathic CoQ₁₀ homolog that has a tail consisting of five isoprene units. It has been used as an electron acceptor to study a range of oxidoreductases as isolated enzymes, in subcellular fractions, in intact cells in culture, and in perfused organs. Ubiquinone analogs, including CoQ₁, impact mitochondrial permeability transition pore (PTP) formation, as well as PTP-dependent cell death, in an analog- and cell-specific manner.

Использование

Coenzyme Q1 is an electron acceptor and a component of the electron transport chain. It also play a role in the?mitochondrial permeability transition pore (PTP). Coenzyme Q1 is structurally similar to?coenzyme Q2 (C636450)?and?coenzyme Q10 (C636501).

Общее описание

Coenzyme Q (CoQ) is localized to the hydrophobic domain of the phospholipid bilayer of mitochondria, plasma lipoproteins, and other biological membranes. It is a ubiquinone homolog with a short isoprenoid side chain.