(S) - (-) - 2-метил-1-бутанол

Химические свойства

clear colourless liquid

Использование

(S)-(-)-2-Methylbutanol can be used as a reactant to prepare:

• Methylbutyl-2-(3-thienyl)acetate (MBTA) by esterification reaction with 3-thiophene acetic acid in the presence of an acid catalyst.
• (2S)-2-Methyl-1-butanesulfenyl chloride by reacting with thioacetic acid using Mitsunobu reaction conditions.
• (+)-Violapyrone C and (-)-myxalamide A.

Определение

ChEBI: The (S)-enantiomer of 2-methylbutan-1-ol.

Общее описание

rest mainly 3-methyl-1-butanol

Методы очистки

Reflux the butanol with CaO, distil, reflux with magnesium and again fractionally distil it. A small sample of highly purified material is obtained by fractional crystallisation after conversion into a suitable ester such as the trinitrophthalate or the 3-nitrophthalate. The latter is converted to the cinchonine salt in acetone and recrystallised from CHCl3 by adding pentane. The salt is saponified, extracted with ether, and fractionally distilled. [Terry et al. J Chem Eng Data 5 403 1960, Beilstein 1 IV 1666.]