ФТОРАЦЕТАМИД

Описание

Fluoroacetamide is an odourless, tasteless, white, crystalline water soluble. It is a fluorinated amide and reacts with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Fluoroacetamide is used as a rodenticide and insecticide to control rabbits but is dangerous for other species of pests, farm livestock, and humans. Fluoroacetamide is a noncombustible substance itself and does not burn but may decompose upon heating to produce irritating, corrosive, and/or toxic fumes. On decomposition, fluoroacetamide releases nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, HF gas, and nitrogen gas.

Химические свойства

Fluoroacetamide is a colorless, crystalline solid.

Использование

Rodenticide. Insecticide proposed mainly for use on fruits to combat scale insects, aphids, and mites.

Определение

ChEBI: Acetamide substituted at C-2 by a fluorine atom.

Методы производства

Fluoroacetamide is produced by reaction of α-chloroacetamide with potassium fluoride in tetrachloroethylene at elevated temperature.

Общее описание

Colorless crystalline powder. Used as a rodenticide. Highly toxic.

Реакции воздуха и воды

Very soluble in water [Farm Chemicals]

Профиль реактивности

FLUOROACETAMIDE is a fluorinated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Опасность

Extremely toxic; poison; mutagen.

Угроза здоровью

FLUOROACETAMIDE is super toxic; probable oral lethal dose in humans is less than 5 mg/kg, or a taste (less than 7 drops) for a 150-lb. person. Chemically inhibits oxygen metabolism by cells with critical damage occurring to the heart, brain, and lungs resulting in heart failure, respiratory arrest, convulsions, and death.

Пожароопасность

Emits very toxic fumes of fluorine containing compounds and nitrogen oxides when heated to decomposition. Avoid decomposing heat.

Профиль безопасности

A human poison by an unspecified route. Poison experimentally by ingestion, skin contact, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects by unspecified route: convulsions, coma, nausea and vomiting. Experimental reproductive effects. Mutation data reported. Used as an insecticide and rodenticide. When heated to decomposition it emits very toxic fumes of Fand NOx. See also FLUORIDES.

Возможный контакт

This material is an organofluorine rodenticide; insecticide proposed mainly for use on fruits to combat scale insects, aphids, and mites. Use is largely restricted to licensed pest control operators.

Перевозки

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Методы очистки

Crystallise fluoroacetamide from chloroform and dry it in a vacuum. [Beilstein 2 IV 454.]

Несовместимости

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explo sions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Утилизация отходов

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations govern ing storage, transportation, treatment, and waste disposal.