Ундекандиовая кислота

Химические свойства

white to light yellow powder

Использование

Undecanedioic Acid is a bioactive compound found in Polygala tenuifolia root which is used as a functional food due to its attractive health benefits.

Определение

ChEBI: An alpha,omega-dicarboxylic acid that is nonane with two carboxylic acid groups at positions C-1 and C-9.

Синтез

Undecanedioic acid is obtained by reacting α -nitro ketone and NaOH in MeOH.To a solution of α -nitro ketone (0.7 mmol) in MeOH (4.2 ml), 25 ml of 0.5 M Na2HPO4 in a 1 N of NaOH were added and the resulting mixture was heated at 70 °C for 1-4 h, then Oxone (1.75 mmol) in water (3 ml) was added to the cold solution (r. t.). After 4 h the mixture was diluted with brine (10 ml), acidified to pH=2 with a 10% solution of HCl and extracted with EtOAc (3 x 20 ml). The combined organic layers were washed with brine (10 ml), dried over Na2SO4 and evaporated to yield pure dicarboxylic acid.

Fig The synthetic method 2 of Undecanedioic acid.

Источник

Undecanedioic acid is a natural product found in Aloe africana, Phaseolus vulgaris, and other organisms with data available.