Основные атрибуты  химическое свойство Информация о безопасности химические свойства, назначение, производство запасные части и сырье поставщик Обзор
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Thiamine nitrate

  • русский язык имя
  • английское имяThiamine nitrate
  • CAS №532-43-4
  • CBNumberCB2472353
  • ФормулаC12H17N5O4S
  • мольный вес327.36
  • EINECS208-537-4
  • номер MDLMFCD00036330
  • файл Mol532-43-4.mol
химическое свойство
Температура плавления 374-392 °C
плотность 1.58 g/cm3
температура хранения 2-8°C
растворимость Sparingly soluble in water, freely soluble in boiling water, slightly soluble in alcohol and in methanol.
форма solid
пка 4.8(at 25℃)
цвет White to Off-White
Запах wh. cryst. or cryst. powd., sl. char. odor
Биологические источники synthetic
Мерк 14,9295
БРН 3857790
Стабильность Stable. Incompatible with strong oxidizing agents.
InChI InChI=1S/C12H17N4OS.NO3/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;2-1(3)4/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);/q+1;-1
ИнЧИКей UIERGBJEBXXIGO-UHFFFAOYSA-N
SMILES [N+]1(CC2=CN=C(C)N=C2N)C(C)=C(SC=1)CCO.[N+]([O-])([O-])=O
FDA 21 CFR 184.1878; 582.5878
Вещества, добавляемые в пищу (ранее EAFUS) THIAMINE MONONITRATE
Специальный комитет по веществам GRAS Thiamine mononitrate
Справочник по базе данных CAS 532-43-4(CAS DataBase Reference)
Рейтинг продуктов питания EWG 1
FDA UNII 8K0I04919X
Система регистрации веществ EPA Thiamine nitrate (532-43-4)
UNSPSC Code 41116107
NACRES NA.79
больше
Заявления об опасности и безопасности
Заявления о безопасности 22-24/25
WGK Германия 1
RTECS XI7400000
TSCA Yes
кода HS 29362200

Thiamine nitrate химические свойства, назначение, производство

Описание

Thiamine is a water-soluble vitamin with antioxidant, neuroprotective, and anxiolytic properties. It inhibits lipid peroxidation in rat liver microsomes and free radical oxidation of oleic acid in vitro when used at concentrations ranging from 1 to 100 μM. In vivo, thiamine (100 mg/kg) reduces hepatic levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), lipid peroxidation, and protein damage in a rat model of acute ethanol intoxication. It reverses predator stress-induced suppression of hippocampal neurogenesis and decreases the latency of step-down from a platform, indicating anxiolytic-like activity in mice. Thiamine (8.5 mg/100 g food) reduces neurodegeneration and increases survival in Slc19a3-/- mice, a model of thiamine metabolism dysfunction syndrome-2 (THMD-2).

Химические свойства

White or almost white, crystalline powder or small, colourless crystals.

Использование

Thiamine Nitrate is an orally administered vitamin. Thiamine is a essential nutrient required for carbohydrate metabolism and is involved in nerve function.

преимущество

Some of the critical uses and benefits of Vitamin B1 Mononitrate(Thiamine nitrate) include:
Supports Energy production: Thiamine nitrate is involved in converting food into energy, particularly in the metabolism of carbohydrates.
Helps Nervous system: Thiamine nitrate is essential for proper nervous system function and is involved in transmitting nerve impulses.
Improves Cardiovascular health: Thiamine nitrate is important for maintaining healthy heart function, and may help to reduce the risk of heart disease.
Supports Appetite regulation: Vitamin B1 mononitrate is involved in regulating appetite and may help to reduce the risk of overeating and weight gain.
Improves Eye health: Thiamine nitrate is involved in maintaining healthy eye function, and may help to reduce the risk of certain eye disorders.

Общее описание

Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Thiamine Nitrate is a mononitrate salt of thiamine. It is synthesized from thiamine hydrochloride following a sequence of steps. Thiamine Nitrate is used as a dietary supplement in crackers, eggs substitute and enriched flour.

Профиль безопасности

Poison by intravenous and intraperitoneal routes. A powerful oxidizer. When heated to decomposition it emits very toxic fums of SOx, and NOx. See also NITRATES.

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