2-ГЕКСАНОН

Описание

2-Hexanone has been used as a solvent for both cellulose- and resin-based coating systems. In the early 1970s, a number of workers in the print department of a coated fabrics plant developed severe peripheral neuropathy from an unknown cause. In search of an etiological agent, and in the absence of other neurotoxicants, 2-hexanone was implicated as it was recently substituted for methyl isobutyl ketone in the manufacturing process. Similar observations in workers exposed to 2-hexanone may have resulted in the decline in production and use in the United States.

Химические свойства

2-Hexanone is a colorless to pale yellow liquid with a sharp odor. It dissolves very easily in water and is miscible in ethanol, methanol, and benzene. 2-Hexanone evaporates easily into the air as a vapor. It is stable, flammable, and incompatible with oxidizing agents, strong bases, and reducing agents. 2-Hexanone is a waste product of wood pulping, coal gasifi cation, and oil shale operations. Formerly, 2-hexanone was in use as a paint and paint thinner with other chemical substances, and to dissolve oils and waxes.and is used as a solvent and organic syn- thesis intermediates. However, the industrial uses of 2-hexanone is now very much restricted.

Физические свойства

Clear, colorless to pale yellow, flammable liquid with an odor resembling acetone and 2-butanone. Nagata and Takeuchi (1990) reported an odor threshold concentration of 24 ppb_v. Amoore and Hautala (1983) reported odor threshold concentrations of 250 μg/L and 76 ppb_v in water and air, respectively.

Использование

2-Hexanone is used in various organic chemical syntheses. It is used in the synthesis of (+/-)-monomorine. It is also used in the preparation of alcohols by transfer hydrogenation of ketones.

Методы производства

MnBK can be produced by a reaction between acetic acid and ethylene under pressure MnBK can be produced by a reaction between acetic acid and ethylene under pressure.

Общее описание

A clear colorless liquid. Flash point 95°F. Less dense than water. Vapors heavier than air.

Реакции воздуха и воды

Highly flammable. Slightly soluble in water.

Профиль реактивности

2-Hexanone is incompatible with oxidizing agents. 2-Hexanone may also react with strong bases and reducing agents.

Опасность

Flammable, moderate fire risk, explosive limits 1.2–8% in air. Irritant to eyes and mucous membranes, narcotic in high concentration, absorbed by skin. Causes peripheral neuropathy and testicular damage.

Угроза здоровью

Inhalation of high concentrations of vapor may result in narcosis; peripheral neuropathy may develop. Ingestion of large amounts may cause some systemic injury. Contact with eyes causes mild to moderate irritation. Liquid irritates skin; prolonged or repeated contact may cause defatting of the skin with resultant dermatitis.

Пожароопасность

2-Hexanone is flammable.

Возможный контакт

The material is used as a solvent

Экологическая судьба

Biological. Using the BOD technique to measure biodegradation, the mean 5-d BOD value (mM BOD/mM 2-hexanone) and ThOD were 5.22 and 61.4%, respectively (Vaishnav et al., 1987).
Photolytic. A second-order photooxidation rate constant of 8.97 x 10^-12 cm³/molecule?sec for the reaction of 2-hexanone and OH radicals in the atmosphere at 299 K was reported by Atkinson (1985).
Chemical/Physical. 2-Hexanone will not hydrolyze because it has no hydrolyzable functional group (Kollig, 1995).

хранилище

2-Hexanone should be kept stored in a tightly closed container, in a cool, dry place, away from sources of ignition.

Перевозки

UN1224 Ketones, liquid, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid, Technical Name Required

Утилизация отходов

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

Меры предосторожности

Occupational workers should be careful when using and handling 2-hexanone. Workers should wash thoroughly after handling the chemical substance. Workers should avoid contact of 2-hexanone with the eyes, skin, and clothing and also avoid contact with heat, sparks, and flame.