Кадралазин
- английское имяCadralazine
- CAS №64241-34-5
- CBNumberCB1398719
- ФормулаC12H21N5O3
- мольный вес283.33
- номер MDLMFCD00865833
- файл Mol64241-34-5.mol
химическое свойство
| Температура плавления | 160-162° |
| Температура кипения | 425.88°C (rough estimate) |
| плотность | 1.1585 (rough estimate) |
| показатель преломления | 1.6500 (estimate) |
| температура хранения | 2-8°C |
| растворимость | DMSO : 250 mg/mL (882.36 mM; ultrasonic and warming and heat to 60°C) |
| форма | Solid |
| пка | 6.0(at 25℃) |
| цвет | White to off-white |
| Справочник по базе данных CAS | 64241-34-5 |
| FDA UNII | 8T96I3U713 |
| Код УВД | C02DB04 |
| Токсичность | LD50 in rats, dogs (mg/kg): 269, approx 400 i.v.; 2060, >2000 orally (Semeraro); in mice (mg/kg): 700 i.p. (Parravicini) |
Кадралазин химические свойства, назначение, производство
Описание
Cadralazine is a vasodilatory antihypertensive reportedly better-tolerated and longer-acting than hydralazine. It is useful as a second-line treatment in the management of hypertension.Всемирная организация здравоохранения(ВОЗ)
Cadralazine, a peripheral vasodilator, was introduced in 1989 for the treatment of arterial hypertension.In 1992, its association with serious side effects led to the refusal of registration in Norway. Animal experiments have demonstrated drug-related impairment of thyroid function as well as potential carcinogenicity and genotoxicity. It remains available for treatment of hypertension in Italy.Кадралазин запасные части и сырье
Кадралазин поставщик
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