Cholesteryl hemisuccinate
- русский язык имя
- английское имяCholesteryl hemisuccinate
- CAS №1510-21-0
- CBNumberCB0336321
- ФормулаC31H50O4
- мольный вес486.73
- EINECS216-148-6
- номер MDLMFCD00037705
- файл Mol1510-21-0.mol
химическое свойство
| Температура плавления | 178 °C |
| Температура кипения | 586.0±43.0 °C(Predicted) |
| плотность | 1.06±0.1 g/cm3(Predicted) |
| показатель преломления | -34 ° (C=2, CHCl3) |
| температура хранения | -20°C |
| растворимость | Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated) |
| форма | Solid |
| пка | 4.40±0.17(Predicted) |
| цвет | White to Off-White |
| ИнЧИКей | WLNARFZDISHUGS-BLYFUZNHSA-N |
| LogP | 10.708 (est) |
| Справочник по базе данных CAS | 1510-21-0(CAS DataBase Reference) |
| FDA UNII | T3J4KS4201 |
| UNSPSC Code | 12352103 |
| NACRES | NA.25 |
Cholesteryl hemisuccinate химические свойства, назначение, производство
Описание
Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity. It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 μM, respectively. Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes. It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts.Использование
Cholesteryl Hemisuccinate is an oxidation product of polyunsaturated fatty acid of cholesterol that alters lysosome structure and functions and induces proinflammatory cytokine production in macrophages.Общее описание
Cholesteryl hemisuccinate (CHEMS) is an acidic cholesterol ester.Cholesteryl hemisuccinate запасные части и сырье
Cholesteryl hemisuccinate поставщик
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