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Альфа-D-лактоза моногидра
- английское имяAlpha-D-Lactose monohydrate
- CAS №5989-81-1
- CBNumberCB0177832
- ФормулаC12H24O12
- мольный вес360.31
- EINECS611-913-4
- номер MDLMFCD00150747
- файл Mol5989-81-1.mol
химическое свойство
Температура плавления | 219 °C |
Температура кипения | 412.35°C (rough estimate) |
альфа | [α]D20+52.2~+52.8° |
плотность | 1,53 g/cm3 |
RTECS | OD9625000 |
показатель преломления | 1.6480 (estimate) |
температура хранения | Inert atmosphere,Room Temperature |
растворимость | H2O: soluble1M, clear, colorless |
форма | Solid |
цвет | White to Off-White |
РН | pH (50g/l, 25℃) : 4.0~6.0 |
Растворимость в воде | Soluble in water. |
Стабильность | Hygroscopic |
ИнЧИКей | WSVLPVUVIUVCRA-KPKNDVKVSA-N |
Справочник по базе данных CAS | 5989-81-1(CAS DataBase Reference) |
Рейтинг продуктов питания EWG | 1 |
FDA UNII | EWQ57Q8I5X |
Система регистрации веществ EPA | .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, hydrate (1:1) (5989-81-1) |
Коды опасности | Xi | |||||||||
Заявления о рисках | 40-36/37/38 | |||||||||
Заявления о безопасности | 24/25-36-26 | |||||||||
WGK Германия | 3 | |||||||||
TSCA | Yes | |||||||||
кода HS | 17021100 | |||||||||
NFPA 704: |
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Альфа-D-лактоза моногидра химические свойства, назначение, производство
Химические свойства
White powderИспользование
alpha-D-Lactose monohydrate is used as a carrier and stabiliser of aromas, pharmaceutical products, Food industry.Определение
A sugar that occurs in many plants. It is extracted commercially from sugar cane and sugar beet. Sucrose is a disaccharide formed from a glucose unit and a fructose unit. It is hydrolyzed to a mixture of fructose and glucose by the enzyme invertase. Since this mixture has a different optical rotation (levorotatory) than the original sucrose, the mixture is called invert sugar.Методы производства
A suspension of a-lactose monohydrate crystals in a lactose solution is atomized and dried in a spray drier. Approximately 10–20% of the total amount of lactose is in solution and the remaining 80–90% is present in the crystalline form. The spray-drying process predominantly produces spherical particles. The compactibility of the material and its flow characteristics are a function of the primary particle size of the lactose monohydrate and the amount of amorphous lactose.Фармацевтические приложения
Spray-dried lactose is widely used as a binder, filler-binder, and flow aid in direct compression tableting.Безопасность
Lactose is widely used in pharmaceutical formulations as a diluent in oral capsule and tablet formulations. It may also be used in intravenous injections.Adverse reactions to lactose are largely due to lactose intolerance, which occurs in individuals with a deficiency of the enzyme lactase.
хранилище
Spray-dried lactose should be stored in a well-closed container in a cool, dry place.Несовместимости
Lactose is a reducing sugar. The amorphous lactose, which is the most reactive form of lactose present in spray-dried lactose, will interact more readily than conventional crystalline grades. Typical reactions include the Maillard reaction with either primary or secondary amines.Альфа-D-лактоза моногидра поставщик
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