What are the biological functions of uridine 5’-diphosphate disodium salt (UDP-Na2)?

Uridine 5'-diphosphate disodium salt (UDP- Na2) is a fundamental building block of RNA biosynthesis. After phosphorylation to uridine triphosphate (UTP), it serves as a substrate for various enzymes, including RNA polymerase, which is involved in the transcription of genetic information. UDP-Na2 plays a crucial role in carbohydrate metabolism, participating in glycosylation, which is essential for the formation of glycoproteins and glycolipids. As a signaling molecule, UDP-Na2 can interact with specific purinergic receptors (such as the P2Y6 receptor), thereby influencing a range of cellular activities, such as inflammatory responses and cytoskeleton dynamics. It is a potent and selective natural agonist of the P2Y6 receptor.

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