Abemaciclib:Drug class, Brand name, Uses and Diet recommendations
Abemaciclib is a type of cancer growth blocker that targets the proteins cyclin dependant kinase 4 and 6 (CDK4 and CDK6) on breast cancer cells.
Drug class
Abemaciclib is a targeted cancer drug.
Brand name
VERZENIO®
Uses
Abemaciclib is a kinase inhibitor indicated:
• in combination with endocrine therapy (tamoxifen or an aromatase inhibitor) for the adjuvant treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, node-positive, early breast cancer at high risk of recurrence.
• in combination with an aromatase inhibitor as initial endocrine based therapy for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer.
• in combination with fulvestrant for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer with disease progression following endocrine therapy.
• as monotherapy for the treatment of adult patients with HR positive, HER2-negative advanced or metastatic breast cancer with disease progression following endocrine therapy and prior chemotherapy in the metastatic setting.[1]
How does it work?
Abemaciclib blocks proteins known as CDK (cyclin dependent kinase) 4 and 6. When activity of CDK 4 and 6 is increased, there is a loss of cell cycle control that leads to increased cell growth and division. By blocking CDK 4 and 6, abemaciclib disrupts breast cancer cell growth and slows tumor progression.
Side Effects
Side Effects of Verzenio (abemaciclib):
• Diarrhea
• Fatigue or tiredness
• Nausea, vomiting
• Headache
• Hair thinning or hair loss
• Rash
• Cough
• Infections
• Low blood counts
• Decrease in white blood cells that fight infection
• Decrease in red blood cells that deliver oxygen throughout the body
• Decrease in platelets that help blood to clot.
Diet recommendations
• Eat a bland diet that is easy to digest until diarrhea resolves
• BRAT diet: bananas, rice, applesauce, toast
• Do not eat high fiber foods (raw vegetables/fruits, whole grains, nuts, seeds, beans)
• Do not have dairy, alcohol, caffeine, spicy and fried foods
Stay Hydrated:
• Drink 8-10 glasses (64-80 ounces) of non-caffeinated, non-carbonated beverages daily
• Gatorade, Pedialyte, or other beverages with electrolytes may be recommended with severe diarrhea
Reference
[1]Mass General Cancer Center
Related articles And Qustion
Lastest Price from Abemaciclib manufacturers

US $5.00-0.50/KG2025-06-05
- CAS:
- 1231929-97-7
- Min. Order:
- 1KG
- Purity:
- 99% hplc
- Supply Ability:
- 500TONS

US $5.00-0.50/KG2025-05-29
- CAS:
- 1231929-97-7
- Min. Order:
- 1KG
- Purity:
- 99% hplc
- Supply Ability:
- 500TONS