I-BET 151

中文名称7-(3,5-二甲基异噁唑-4-基)-8-甲氧基-1-((R)-1-(吡啶-2-基)乙基)-1H-咪唑并[4,5-C]喹啉-2(3H)-酮中文同义词7-(3,5-二甲基异恶唑-4-基)-8-甲氧基-1-((R)-1-(吡啶-2-基)乙基)-1H-咪唑并[4,5-C]喹啉-2(3H)-酮;7-(3,5-二甲基异噁唑-4-基)-8-甲氧基-1-((R)-1-(吡啶-2-基)乙基)-1H-咪唑并[4,5-C]喹啉-2(3H)-酮;7-(3,5-二甲基-4-异噁唑基)-1,3-二氢-8-甲氧基-1-[(1R)-1-(2-吡啶基)乙基]-2H-咪唑并[4,5-C]喹啉-2-酮;1-(2-吡啶基)乙基]-2H-咪唑并[4,5-C]喹啉-2-酮;7-(3,5-二甲基-4-异唑基)-1,3-二氢-8-甲氧基-1-[(1R)-1-(2-吡啶基)乙基]-2H-咪唑并[4,5-C]喹啉-2-酮;化合物I-BET151;化合物TG100713;I-BET151,异恶唑类PAN-BET家族抑制剂

英文名称I-BET151(GSK1210151A)英文同义词7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one;I-BET151/GSK1210151A;GSK1210151A(I-BET151);7-(3,5-diMethylisoxazol-4-yl)-8-Methoxy-1-((R)-1-(pyridin-2-yl)ethyl)-1H-iMidazo[4,5-c]quinolin-2(3H)-one;7-(3,5-Dimethylisoxazol-4-yl)-8-methoxy-1-((R)-1-(pyridin-2-yl)ethyl)-1H-imidazo[4,5-c]quinolin-2;GSK1210151A;I-BET151;7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-oneI-BET151(GSK1210151A)CAS号1300031-49-5分子式C23H21N5O3分子量415.44

7-(3,5-二甲基异噁唑-4-基)-8-甲氧基-1-((R)-1-(吡啶-2-基)乙基)-1H-咪唑并[4,5-C]喹啉-2(3H)-酮性质密度1.314储存条件2-8°C溶解度在DMSO中的溶解度为20mg/mL，澄清形态粉末酸度系数(pKa)11.14±0.20(Predicted)颜色白色至米色