α-芋螺毒素MII，α-Conotoxin MII，175735-93-0，杭州固拓生物多肽物美价廉 新品

Product Name：α-Conotoxin MII（α-CTxMII）

Synonyms：α-Conotoxin MII

CAS No.：175735-93-0

Catalog No.：GT-XL0203

Brand：Go Top peptide（杭州固拓）

Description：α-Conotoxin MII最初从海洋腹足类动物僧袍芋螺（Conus magus）毒液中分离得到的天然多肽毒素。α-Conotoxin MII为nAChR高选择性竞争性拮抗剂，强效抑制α3β2亚型（IC₅₀=0.5 nM），同时可抑制含β3亚基的神经元烟碱受体；对α3β2的亚型选择性远超α2β2、α4β2、α3β4达200倍以上，是研究神经传递、成瘾、疼痛机制的科研工具肽。

α-Conotoxin MII is a natural peptide toxin originally isolated from the venom of the marine gastropod Conus magus. α-Conotoxin MII is a highly selective competitive antagonist of nAChRs, strongly inhibiting the α3β2 subtype (IC₅₀ = 0.5 nM) while also inhibiting neuronal nicotinic receptors containing the β3 subunit; its subtype selectivity for α3β2 is more than 200 times greater than for α2β2, α4β2, and α3β4, making it a research tool peptide for studying neural transmission, addiction, and pain mechanisms.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H2O/DMSO

Vacuum-packedwith aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	GCCSNPVCHLEHSNLC-NH2(Disulfidebridge:Cys2-Cys8,Cys3-Cys16)
Sequence(3-letter code)	H-Gly-Cys-Cys-Ser-Asn-Pro-Val-Cys-His-Leu-Glu-His-Ser-Asn-Leu-Cys-NH2(Disulfidebridge:Cys2-Cys8,Cys3-Cys16)
Peptide Structure
Molecular Formula	C67H103N23O22S4
Molecular Weight	1710.94

申明：产品仅供科研使用，不得用于人体。

订购联系方式：

手机：+86-15572296305  +86-18157160292 肖经理（同微信号）    

QQ:  2080293014   3856537783  

邮箱：sales4@gotopbio.com