α-芋螺毒素MII/175735-93-0/α-Conotoxin MII 新品

Product Name：α-Conotoxin MII

CAS No.：175735-93-0

Synonyms：α-芋螺毒素 MII

Catalog No.：218P092

Brand：Typeptide Biotech（肽研生物）

Description：α-Conotoxin MII是一种高效的选择性竞争性拮抗剂多肽，多肽序列中包含16个氨基酸，具有两对二硫键结构，可用于含 α3β2 亚基的烟碱受体（在非洲爪蟾卵母细胞中表达的 α3β2 处，IC50 = 0.5 - 3.5 nM），还有效阻断含 β3 的神经元烟碱受体。α-Conotoxin MII与 α2β2、α4β2 和 α3β4 相比，α3β2 的选择性超过 200 倍，是一种极具前景的拮抗剂多肽。

α-Conotoxin MII is a highly potent and selective competitive antagonist peptide containing 16 amino acids in its sequence, featuring two pairs of disulfide bonds. It effectively targets nicotinic receptors with α3β2 subunits (IC50 = 0.5–3.5 nM in Xenopus oocytes expressing α3β2), as well as neuronal nicotinic receptors containing β3. Compared to α2β2, α4β2, and α3β4, α-Conotoxin MII exhibits over 200-fold selectivity for α3β2, making it a highly promising antagonist peptide.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

南京肽研生物生物科技有限公司

手机号：19961912513(微信同号)

QQ: 2178255659

邮箱：sales@typeptide.com

联系人：顾经理

申明：本产品仅供科研使用，不得用于人体。