α-芋螺毒素MII/175735-93-0/α-Conotoxin MII

Product Name：α-Conotoxin MII

CAS No.：175735-93-0

Synonyms：α-芋螺毒素 MII

Catalog No.：218P092

Brand：HongTide（上海鸿肽生物）

Description：α-Conotoxin MII是一种高效的选择性竞争性拮抗剂多肽，多肽序列中包含16个氨基酸，具有两对二硫键结构，可用于含 α3β2 亚基的烟碱受体（在非洲爪蟾卵母细胞中表达的 α3β2 处，IC50 = 0.5 - 3.5 nM），还有效阻断含 β3 的神经元烟碱受体。α-Conotoxin MII与 α2β2、α4β2 和 α3β4 相比，α3β2 的选择性超过 200 倍，是一种极具前景的拮抗剂多肽。

α- Conotoxin MII is a highly effective selective competitive antagonist peptide that contains 16 amino acids and has two pairs of disulfide bond structures, which can be used to contain α three β Nicotinic receptor subunit 2 (expressed in Xenopus laevis oocytes) α three β 2 locations, IC50=0.5 - 3.5 nM), also effectively blocking the presence of β Nicotine receptors in neurons of 3. α- Conotoxin MII and α two β 2、 α four β 2 and α three β 4 Compared to, α three β 2 has a selectivity of over 200 times and is a promising antagonist peptide.

Purity (HPLC) ≥95.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

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