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  • 苦木素|TN2120|TargetMol

苦木素|TN2120|TargetMol

Quassin
￥7900 5mg 起订
￥2130 1mg 起订
￥11800 10mg 起订
上海 更新日期：2026-05-08

TargetMol 中国（陶术生物）

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邮箱：xuexiang.shao@tsbiochem.com

产品详情:

中文名称：
苦木素
英文名称：
Quassin
CAS号：
76-78-8
品牌：
TargetMol
产地：
美国
保存条件：
Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
产品类别：
抑制剂
货号：
TN2120

Product Introduction

Bioactivity

名称Quassin
描述Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion.
体外活性An HPLC method was employed for purification of the biologically active Quassinoids; Quassin (Q) and neo-Quassin (NQ), further characterized by MALDI-TOF analyses. Purified Q, NQ and the crude bark extract (S1) along with artesunate (AS) were studied for their in vitro anti-plasmodial activity. The in vivo toxicity studies at intraperitoneal doses with higher concentrations of the crude bark extract (S1) in Balb/C mice ruled out the apprehension of toxicity. Interaction studies between the test compounds among themselves (Q+NQ) and individually with artesunate (AS+Q, AS+NQ), were carried out in vitro at four ratios (1:5, 1:2, 2:1 and 5:1) on chloroquine sensitive (MRC-pf-20) and resistant (MRC-pf-303) strains of Plasmodium falciparum. The crude bark extracts of Q. amara exhibited higher P. falciparum inhibitory activity (IC(50)=0.0025 microg/ml) as compared to that of the isolated compounds, Quassin (IC(50)=0.06 microg/ml, 0.15 microM), neo-Quassin (IC(50)=0.04 microg/ml, 0.1 microM) and also to the positive control, artesunate (IC(50)=0.02 microg/ml, 0.05 microM)[1]
存储条件Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
关键字Quassin | NO Synthase | Estrogen Receptor/ERR | Antifection
相关产品2-Amino-2-methyl-1-propanol | Urethane | Fenpyroximate | Flubendazole | Coumaran | Doxycycline | Metronidazole | Methylene Blue trihydrate | Hydroxychloroquine | Gum arabic | Benzimidazole | Kojic acid
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苦木素|TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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