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网站主页化工产品目录天然产物生物碱肉叶云香碱哈尔明 98%, 去氢骆驼蓬碱, 陕西永源生物

哈尔明 98%, 去氢骆驼蓬碱, 陕西永源生物

Harmine 98%
442-51-3

陕西更新日期：2017-10-10

陕西永源生物技术有限公司

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产品详情:

中文名称：: 哈尔明 98%, 去氢骆驼蓬碱, 陕西永源生物

英文名称：: Harmine 98%

CAS号：: 442-51-3

品牌：: Yongyuan Bio-Tech

产地：: 中国

纯度规格：: 98%

品名：去氢骆驼蓬碱,哈尔明

英文名称: Harmine

别名：哈尔明碱、肉叶云香碱、去氢骆驼蓬碱

结构式：

分子式：C13H12N2O

分子质量：236.7

CAS：442-51-3

产品规格：98%HPLC

产品性状：淡黄色

理化性质：熔点 262-264 °C(lit.)

提取来源：蒺藜科骆驼蓬属植物骆驼蓬Peganum harmala L.的种子。

主要应用：骆驼蓬的药理作用十分广泛，主要对中枢神经、心血管系统、肌肉、离子通道有作用，还有抗菌、降低体温的作用。近年来的研究还发现它有以下药理作用。

1)防辐射作用。

2)抗包虫作用。

3)抗炎、镇痛及止痒作用。

4)抑制细胞免疫和体液免疫的作用。

5)抗银屑病作用。

6)抗肿瘤作用。

包装： 1公斤/铝箔袋；或根据客户需求

保存：置于阴凉干燥、避光，避高温处

有效期： 24个月

Product name: Harmine

Latin name: Peganum harmala L.

Part Used:Seed

Specification: Harmine 98%HPLC

CAS No:442-51-3

Molecular Formula:C13H12N2O
Molecular Weight:236.7
Melting Point:262-264 °C(lit.)

Appearance: Light Yellow fine powder

Description:

Harmine, also known as telepathine, is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds. It occurs in a number of different plants, most notably the Middle Eastern plant harmal or Syrian rue (Peganum harmala) and the South American vine Banisteriopsis caapi (also known as "yage" or "ayahuasca"). Harmine reversibly inhibits monoamine oxidase A (MAO-A), an enzyme which breaks down monoamines, making it a RIMA. Harmine selectively binds to MAO-A but does not inhibit the variant MAO-B.

Function:

Monoamines include neurotransmitters (serotonin, dopamine), hormones (melatonin, epinephrine, norepinephrine) and psychedelic drugs (psilocybin, DMT and mescaline). By slowing the breakdown of neurotransmitters, monoamine oxidase inhibitors (MAOIs) can help to replenish the body's supply of these chemicals, and many MAOIs are used as antidepressants. Harmine has not been the subject of much clinical research in the treatment of depression, which could be due in part to its restricted legal status in many countries, as well as the existence of synthetic MAOIs with fewer side effects.

P. harmala and B. caapi are both traditionally used for their psychoactive effects. B. caapi has a tradition of use in conjunction with plants containing the drug DMT. Traditionally, B. caapi is consumed as a drink, with or without the DMT-bearing plants (see Ayahuasca). Ordinarily, DMT is not active when taken orally, but users report very different effects when MAOIs are present in such beverages. Harmine and substances containing it have been used in conjunction with many other drugs by modern experimenters. Many hallucinogens appear to exhibit increased potency when used in this way.

Harmine is also a useful fluorescent pH indicator. As the pH of its local environment increases, the fluorescence emission of harmine decreases.

With the radioisotope carbon-11 harmine is used in positron emission tomography neuroimaging to examine its binding to MAO-A.

Harmine found in root secretions of Oxalis tuberosa has been found to have insecticidal properties.

Harmine has been found to increase EAAT2 glutamate pump expression in central nervous system, therefore reducing glutamate toxicity.

Anticancer

Harmine showed cytotoxicity against HL60 and K562 cell lines. This could explain the cytotoxic effect of P. harmala on these cells.

Effects on bone and cartilage

Harmine was shown to promote differentiation of osteoblasts (bone-forming cells), and chondrocytes (cells in the cartilage).

It was also shown to inhibit osteoclastogenesis (the formation of bone resorbing cells).

Storage: Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation

Shelf life: 2 year when properly stored.

Packing:1KG/Bag.

去氢骆驼蓬碱,哈尔明, Harmine, CAS：442-51-3, Shaanxi yongyuan Bio

公司简介

陕西永源生物技术有限公司专注于植物提取物，天然甜味剂，天然色素，动物提取物和微生物发酵等天然产品的研发，生产和销售。面向全球经营，致力于提供高品质的天然原料。

成立日期	(16年)
注册资本	100万
员工人数
年营业额
经营模式	工厂,定制
主营行业	植物提取物