模仿肽ATX-GD-59；杭州固拓生物多肽合成

Product Name：ATX-GD-59

Synonyms：模仿肽ATX-GD-59

CAS No.：暂无公开的CAS登记号

Catalog No.：GT-XL0061

Brand：Go Top peptide（杭州固拓）

Description：ATX-GD-59是首个进入临床、靶向TSHR的肽类apitope，通过“诱导抗原特异性免疫耐受”机制，在Graves病治疗中显示出良好安全性与70%早期响应率。若后续随机对照试验证实其长期缓解优势，有望成为近60年来首个病因修饰型新疗法。

ATX-GD-59 is the first peptide apitope targeting TSHR to enter clinical trials. Through the mechanism of 'inducing antigen-specific immune tolerance,' it has shown good safety and a 70% early response rate in the treatment of Graves' disease. If subsequent randomized controlled trials confirm its long-term remission benefits, it could become the first disease-modifying therapy in nearly 60 years.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H2O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	KKKKYVSIDVTLQQLESHKKK
Sequence(3-letter code)	H-Lys-Lys-Lys-Lys-Tyr-Val-Ser-Ile-Asp-Val-Thr-Leu-Gln-Gln-Leu-Glu-Ser-His-Lys-Lys-Lys-OH
Peptide Structure
Molecular Formula	C114H198N32O32
Molecular Weight	2529.26

申明：产品仅供科研使用，不得用于人体。

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