Product Name：ATX-GD-59
CAS No.：N/A
Synonyms：ATX-GD-59 peptide therapy；模仿肽ATX-GD-59
Catalog No.：218P236
Brand：HongTide（上海鸿肽生物）
Description：ATX-GD-59作为药物多肽，是一种基于肽的疗法（peptide therapy），主要生物机理是模仿抗原表位灭活攻击甲状腺的白细胞，阻止抗促甲状腺激素受体（TSHR）刺激性抗体的产生，能够靶向格雷夫斯病的免疫学基础，有望成为60年来首个治疗格雷夫斯病的修饰创新疗法。在临床上，ATX-GD-59治疗格雷夫斯病具有良好的安全性和耐受性，能偶促甲状腺激素受体（TSHR）抗体水平正常。
As a drug peptide, ATX-GD-59 is a peptide therapy. Its main biological mechanism is to mimic the antigen epitope to inactivate the white blood cells attacking the thyroid, prevent the production of anti thyroid hormone receptor (TSHR) stimulating antibodies, and target the immunological basis of Graves disease. It is expected to become the first modified and innovative therapy for Graves disease in 60 years. In clinical practice, ATX-GD-59 has good safety and tolerance in the treatment of Graves disease, and can even cause the level of thyroid hormone receptor (TSHR) antibody to be normal.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | KKKKYVSIDVTLQQLESHKKK |
Sequence(3-letter code) | H-Lys-Lys-Lys-Lys-Tyr-Val-Ser-Ile-Asp-Val-Thr-Leu-Gln-Gln-Leu-Glu-Ser-His-Lys-Lys-Lys-OH |
Peptide Structure | 
|
Molecular Formula | C114H198N32O32 |
Molecular Weight | 2529.26 |
订购联系方式：
上海鸿肽生物科技有限公司
手机： +86-18018095145 （同微信号）
QQ: 3259098395
邮箱：sales1@hongtide.com
