恩夫韦地，159519-65-0，Enfuvirtide

Product Name：Enfuvirtide

Synonyms：T-20,T 20 (peptide),Enfuvirtide,恩夫韦地

CAS No.：159519-65-0

Description：醋酸恩夫韦地于2003年由美国FDA批准,在HIV病毒感染的治疗中与其他抗HIV病毒药物联合应用。恩夫韦地是一种新型抗逆病毒药物,是近7年来抗艾滋病治疗药物的先锋。恩夫韦地模拟HR2域、由HIV-1gp41蛋白衍生而合成的36个氨基酸多肽,为一选择性、有效的HIV-1融合和感染抑制剂,可结合于HR1三聚体螺旋,阻止HR1-HR2六螺旋束的形成,因而防止病毒颗粒与宿主细胞融合。

Enfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake. The first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 fusion with CD4 cells.

Purity (HPLC) ≥95.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Vacuum-packed with aluminum foil bag or transparent bag. 10mg,50mg,100mg,1g,10g, 50g per package with icebag. Or according to your request. 

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.