MBL/MBL2蛋白-ACROBiosystems百普赛斯

MBL产品信息

英文名称：Mannose-binding protein C

中文名称：甘露糖结合蛋白C

靶点别称：MBL,MBL2,MBP1,MBP-C,Collectin-1,COLEC1

物种：Human

属性：Protein

标记：Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

MBL分子背景

甘露糖结合凝集素（MBL）也称为甘露糖结合蛋白、甘露聚糖结合蛋白（MBP）、甘露糖结合蛋白C、凝集素-1（COLEC1）、MBL2，属于C型凝集素超家族中的凝集素类。MBL含有一个C型凝集素结构域和一个胶原样结构域。MBL具有寡聚结构（400-700kDa），由亚基组成，亚基包含三条可能相同的肽链，每条肽链约30kDa。MBL是参与先天免疫防御的钙依赖性凝集素。MBL结合不同微生物上的甘露糖、岩藻糖和N-乙酰葡糖胺，并激活凝集素-补体途径。MBL与晚期凋亡细胞结合。MBL可能会与D结合。