单克隆Anti MMAE&MMAF抗体-ACROBiosystems百普赛斯

Monoclonal Anti-MMAE&MMAF Antibody, Mouse IgG1 (MALS verified)

抗体来源（Source）

Monoclonal Anti-MMAE&MMAF Antibody, Mouse IgG1 is recombinantly produced from human 293 cells (HEK293).

宿主（Host Species）

Mouse

亚型（Isotype）

Mouse IgG1 / kappa

特异性（Specificity）

Specifically recognizes the target-MMAE&MMAF.

抗体类型（Antibody Type）

Recombinant Monoclonal

纯度（Purity）

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

偶联（Conjugate）

Unconjugated

纯化（Purification）

Protein A purified/ Protein G purified

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 24 months in lyophilized state;

-70°C for 12 months under sterile conditions after reconstitution.

背景（Background）

Monomethyl auristatin E (MMAE) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. Anti-MMAE antibody is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: PK, PD, Immunoassay and ELISA.