aladdin 阿拉丁 L126224 OSI-906(Linsitinib),双重IGF-1R和胰岛素受体激酶抑制剂 867160-71-2 ≥99%

中文名：OSI-906(Linsitinib),双重IGF-1R和胰岛素受体激酶抑制剂

英文名：OSI-906 (Linsitinib)

中文别名：顺式-3-[8-氨基-1-(2-苯基-7-喹啉基)咪唑并[1,5-A]吡嗪-3-基]-1-甲基环丁醇

英文别名：Linsitinib|867160-71-2|OSI-906|Linsitinib(OSI-906)|OSI906|OSI 906|OSI-906AA|OSI-906 (Linsitinib)|ASP-7487|3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol|15A52GPT8T|CHEMBL1091644|MMV676605|cis-3-(8-amino-1-(2-phenyl

纯度：≥99%

货号：L126224

包装：10mg、50mg、5mg

Cas号：867160-71-2

存储温度：-20°C储存

产品介绍：

Linsitinib is a potent, selective insulin-like growth factor-1 receptor (IGF-1R, IC50 = 35 nM) and insulin receptor (IR, IC50 = 75 nM) kinase inhibitor which works to block the autophosphorylation of IGF-1R and IR. Additionally, in vitro studies of Linsitinib have demonstrated its ability to inhibit the proliferation of multiple tumor cell lines.Linsitinib is a selective inhibitor of IGF-1R with IC50 of 35 nM, and modestly potent to InsR with IC50 of 75 nM, and has no activity towards Abl, ALK, BTK, EGFR, FGFR1/2, PKA etc.

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