JNJ-28871063 hydrochloride

Name: JNJ-28871063 hydrochloride
CAS#: 944342-90-9
Chemical Formula: C24H28Cl2N6O3
Exact Mass: 518.16
Molecular Weight: 519.43
Elemental Analysis: C, 55.50; H, 5.43; Cl, 13.65; N, 16.18; O, 9.24

Description: JNJ-28871063 hydrochloride is an ErbB receptor family inhibitor that inhibits growth of human cancer cell lines overexpressing ErbB2 and growth of human tumor xenografts.

IUPAC/Chemical Name: (E)-4-amino-6-((4-(benzyloxy)-3-chlorophenyl)amino)pyrimidine-5-carbaldehyde O-(2-morpholinoethyl) oxime hydrochloride

InChi Key: ZXKZRKQMKNRZNN-GZPZNDDGSA-N

InChi Code: InChI=1S/C24H27ClN6O3.ClH/c25-21-14-19(6-7-22(21)33-16-18-4-2-1-3-5-18)30-24-20(23(26)27-17-28-24)15-29-34-13-10-31-8-11-32-12-9-31;/h1-7,14-15,17H,8-13,16H2,(H3,26,27,28,30);1H/b29-15+;

SMILES Code: ClC1=CC(NC2=C(/C=N/OCCN3CCOCC3)C(N)=NC=N2)=CC=C1OCC4=CC=CC=C4.[H]Cl

Appearance: Solid powder