长沙上禾生物Staherb蒿甲醚Artemether应用领域中英文简介

公司官网 http://www.staherb.com/ 资质:HALAL, KOSHER等认证

☎：19573130018 杨经理（微信同号）

中文简介｜Application Fields (CN)

产品：蒿甲醚 Artemether（β-构型为主，青蒿素半合成衍生物）

供应商：长沙上禾生物科技有限公司（Changsha Staherb Natural Ingredients Co., Ltd.）

核心应用领域

1. 抗疟原料药（主业）：用于配制口服常释制剂（片/胶囊）、油悬肌注液（80 mg/1 mL 等）、复方蒿甲醚片等；主治恶性疟、间日疟，重点覆盖抗氯喹恶性疟及凶险型/脑型疟急救。

2. 青蒿素联合疗法（ACTs）组分：作为固定剂量复方前药，与苯芴醇（Lumefantrine）等组成 ACT，用于非重症 falciparum 疟一线治疗，降低复燃与耐药。

3. 兽药与水产抗寄生虫：用于畜禽、水产抗血液孢子虫、球虫及动物疟原虫研究，作饲料添加剂或兽用复方前体（需按目标国兽药法规注册）。

4. 科研与药物开发工具化合物：高纯单体（≥98% HPLC）作 HPLC 对照品、疟原虫铁激活机制、过氧桥药效团、抗肿瘤/抗炎先导物筛选用标准品。

5. 延伸药理研究（非宣称）：在抗血吸虫（日本血吸虫童虫）、抗病毒、免疫调节等临床前研究中作为受试分子，不属于 Staherb 原料页的法定适应证。

⚠️ 原料出口页只写"API for antimalarial formulation / research use"，不要把"治脑型疟""抗血吸虫"当成品药宣称，避免未获批临床声明。

English Profile｜Application Fields (EN)

Product: Artemether (β-artemether predominant, semi-synthetic artemisinin derivative)

Supplier: Changsha Staherb Natural Ingredients Co., Ltd. (Staherb®)

Key Application Fields

1. Antimalarial API (core use): Starting material for oral solid dosage (tablets/capsules), oil-based intramuscular injection (e.g. 80 mg/1 mL), and artemether injection concentrates. Targets P. falciparum and P. vivax, especially chloroquine-resistant falciparum malaria and severe/cerebral malaria rescue when IV artesunate is unavailable.

2. ACT component: Fixed-dose combination partner (most notably artemether–lumefantrine) for uncomplicated falciparum malaria; rapid schizonticide + partner drug clears residual parasitemia and delays resistance.

3. Veterinary & aquaculture antiparasitic: Research/compounding use against animal plasmodia, blood sporozoa, coccidia; feed-additive and vet-formulation precursor under local veterinary registration.

4. Research reagent / reference standard: ≥98% HPLC grade supplied as pharmacopoeial reference, tool compound for endoperoxide pharmacophore studies, heme-iron activation models, and antitumor/anti-inflammatory lead optimization.

5. Preclinical pharmacology studies (non-promotional): Investigated in schistosomiasis (juvenile S. japonicum), antiviral and immune-modulation models — listed as research context only, not Staherb product claims.

Formulation fit: Lipophilic prodrug (cLogP≈2.84), metabolizes via CYP3A4/CYP2B6 to active dihydroartemisinin (DHA); suits oil suspension, softgel, and co-micronized ACT blends.

公司官网 http://www.staherb.com/ 资质:HALAL, KOSHER等认证

☎：19573130018 杨经理（微信同号）