Application: Pharmaceutical/Feed
Xylazine
Hydrochloride is α2 class of adrenergic receptor agonist.Target:
Adrenergic ReceptorXylazine is a drug that is used for sedation,
anesthesia, muscle relaxation, and analgesia in animals such as horses,
cattle and other non-human mammals. it is an agonist at the α2 class of
adrenergic receptor. Xylazine has recently emerged as a recreational
drug, especially in Puerto Rico .
Administration of xylazine (0.17
mg/kg of body weight, diluted to a 10-ml volume, using 0.9% NaCl)
induced approximately 2.5 hours of local analgesia without apparent side
effects. Higher doses of xylazine caused mild hind limb ataxia.
Administration of lidocaine induced a similar duration of analgesia,
with severe hind limb ataxia (100% incidence). We concluded that
xylazine given by epidural injection results in safe, effective perineal
analgesia in horses .
China
