1. Materials information
Names
| Name | N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine |
|---|
| Synonym | More Synonyms |
|---|
Xylazine Biological Activity
| Description | Xylazine is α2 class of adrenergic receptor agonist.Target: Adrenergic ReceptorXylazine is a drug that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. An analogue of clonidine, it is an agonist at the α2 class of adrenergic receptor. Xylazine has recently emerged as a recreational drug, especially in Puerto Rico [1]. Administration of xylazine (0.17 mg/kg of body weight, diluted to a 10-ml volume, using 0.9% NaCl) induced approximately 2.5 hours of local analgesia without apparent side effects. Higher doses of xylazine caused mild hind limb ataxia. Administration of lidocaine induced a similar duration of analgesia, with severe hind limb ataxia (100% incidence). We concluded that xylazine given by epidural injection results in safe, effective perineal analgesia in horses [2]. |
|---|
| Related Catalog | Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease |
|---|
| References | [1]. Reyes, J.C., et al., The emerging of xylazine as a new drug of abuse and its health consequences among drug users in Puerto Rico. J Urban Health, 2012. 89(3): p. 519-26. [2]. Hsu, W.H., Xylazine-induced depression and its antagonism by alpha adrenergic blocking agents. J Pharmacol Exp Ther, 1981. 218(1): p. 188-92. |
|---|
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|
| Boiling Point | 334.2±52.0 °C at 760 mmHg |
|---|
| Melting Point | 140ºC |
|---|
| Molecular Formula | C12H16N2S |
|---|
| Molecular Weight | 220.334 |
|---|
| Flash Point | 155.9±30.7 °C |
|---|
| Exact Mass | 220.103424 |
|---|
| PSA | 49.69000 |
|---|
| LogP | 2.37 |
|---|
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
|---|
| Index of Refraction | 1.611 |
|---|
| Storage condition | −20°C |
|---|
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: sun@fdachem.com
Mob: 86 13526505137
WhatsApp/Skype/Wechat/LINE: 8613526505137
China
