URICASE NEW

The Urate oxidase, with the CAS registry number 9002-12-4, is also known as Uricozyme. It belongs to the product categories of 1.7.x.x Other nitrogenous donors; 1.x.x.x Oxidoreductases; General Metabolic Enzymes; General Metabolic Enzymes I-ZEnzyme Class Index; Metabolomics. Its EINECS number is 232-655-5. Its EC number is 1.7.3.3. Its classification codes are: (1)Drug / Therapeutic Agent; (2)Natural Product; (3)TSCA Flag XU [Exempt from reporting under the Inventory Update Rule]. It should be sealed and stored in a ventilated and dry place. Its storage temperature is -20 °C. Moreover, it should be protected from light. Urate oxidase is mainly localised in the liver, where it forms a large electron-dense paracrystalline core in many peroxisomes. The enzyme exists as a tetramer of identical subunits, each containing a possible type 2 copper-binding site. Urate oxidase is a homotetrameric enzyme containing four identical active sites situated at the interfaces between its four subunits. It can be found in an extensive variety of organisms, from bacteria to mammals, and plays different metabolic roles, depending on its host organism, it is absent in humans and many other primates.

Preparation: with yeast as raw materials, extract with sodium phosphate, then grade with ammonium sulfate. The product is obtained through dialysis, column chromatography, ammonium sulfate recrystallization.

Uses of Urate oxidase: the enzyme Urate oxidase (UO), or uricase or factor-independent urate hydroxylase, catalyzes the oxidation of uric acid to 5-hydroxyisourate.

Uric acid + O₂ + H₂O → 5-hydroxyisourate + H₂O₂ → allantoin + CO₂

COMPANY PROFILE

Hebei yanxi chemical co.,Itd is a professional research and development of the production of lead acetate,2-phenylethylamide enterprises.The key members of the company are established by local well-known entrepreneurs and professional engineers under the call and support of the party's"low-carbon environmental protectionsafety and stability"under the innovation in traditional production equipment and technology,the use of"high temperature cooling"and "plastic basin crystallization"technology,on the basis of reducing the cost of products to make the quality of products to the same industryWith the efforts of all the staff of the companywe have established many cooperative companies in Shan Dong,He Nan,Guang Dong and other places in recent decades. Under the close supervision of the quality inspection department of the company,we carry out production and sales in the way of "labeling",providing the most convenient and fastest service for users all over the countryCompanies in the"advance with The Timesand the city every day with the advancement of"under the guidance of the core ideasadhering to the"relying on scientific and technological innovationthe development of circular economy" of the enterprise purpose,established in the marketenhance strength,go the way of science and environmental sustainable developmentrelying on the national technology research and development center, increasing spending on research and development based on the domestic market, expand the international marketmanufacturing high quality productssincere service society,toward a modern, ecology, science and technologychemical enterprises of the world.